tener un ir con estos códigos:
>>> import pyexcel as pe
>>> sheet = pe.Sheet(data)
>>> data=[[1, 2], [2, 3], [4, 5]]
>>> sheet
Sheet Name: pyexcel
+---+---+
| 1 | 2 |
+---+---+
| 2 | 3 |
+---+---+
| 4 | 5 |
+---+---+
>>> sheet.save_as("one.csv")
>>> b = [[126, 125, 123, 122, 123, 125, 128, 127, 128, 129, 130, 130, 128, 126, 124, 126, 126, 128, 129, 130, 130, 130, 130, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 132, 134, 134, 134, 134, 134, 134, 134, 134, 133, 134, 135, 134, 133, 133, 134, 135, 136], [135, 135, 136, 137, 137, 136, 134, 135, 135, 135, 134, 134, 133, 133, 133, 134, 134, 134, 133, 133, 132, 132, 132, 135, 135, 133, 133, 133, 133, 135, 135, 131, 135, 136, 134, 133, 136, 137, 136, 133, 134, 135, 136, 136, 135, 134, 133, 133, 134, 135, 136, 136, 136, 135, 134, 135, 138, 138, 135, 135, 138, 138, 135, 139], [137, 135, 136, 138, 139, 137, 135, 142, 139, 137, 139, 138, 136, 137, 141, 138, 138, 139, 139, 139, 139, 138, 138, 138, 138, 137, 137, 137, 137, 138, 138, 136, 137, 137, 137, 137, 137, 137, 138, 148, 144, 140, 138, 137, 138, 138, 138, 137, 137, 137, 137, 137, 138, 139, 140, 141, 141, 141, 141, 141, 141, 141, 141, 141], [141, 141, 141, 141, 141, 141, 141, 139, 139, 139, 140, 140, 141, 141, 141, 140, 140, 140, 140, 140, 141, 142, 143, 138, 138, 138, 139, 139, 140, 140, 140, 141, 140, 139, 139, 141, 141, 140, 139, 145, 137, 137, 145, 145, 137, 137, 144, 141, 139, 146, 134, 145, 140, 149, 144, 145, 142, 140, 141, 144, 145, 142, 139, 140]]
>>> s2 = pe.Sheet(b)
>>> s2
Sheet Name: pyexcel
+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+
| 126 | 125 | 123 | 122 | 123 | 125 | 128 | 127 | 128 | 129 | 130 | 130 | 128 | 126 | 124 | 126 | 126 | 128 | 129 | 130 | 130 | 130 | 130 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 132 | 134 | 134 | 134 | 134 | 134 | 134 | 134 | 134 | 133 | 134 | 135 | 134 | 133 | 133 | 134 | 135 | 136 |
+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+
| 135 | 135 | 136 | 137 | 137 | 136 | 134 | 135 | 135 | 135 | 134 | 134 | 133 | 133 | 133 | 134 | 134 | 134 | 133 | 133 | 132 | 132 | 132 | 135 | 135 | 133 | 133 | 133 | 133 | 135 | 135 | 131 | 135 | 136 | 134 | 133 | 136 | 137 | 136 | 133 | 134 | 135 | 136 | 136 | 135 | 134 | 133 | 133 | 134 | 135 | 136 | 136 | 136 | 135 | 134 | 135 | 138 | 138 | 135 | 135 | 138 | 138 | 135 | 139 |
+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+
| 137 | 135 | 136 | 138 | 139 | 137 | 135 | 142 | 139 | 137 | 139 | 138 | 136 | 137 | 141 | 138 | 138 | 139 | 139 | 139 | 139 | 138 | 138 | 138 | 138 | 137 | 137 | 137 | 137 | 138 | 138 | 136 | 137 | 137 | 137 | 137 | 137 | 137 | 138 | 148 | 144 | 140 | 138 | 137 | 138 | 138 | 138 | 137 | 137 | 137 | 137 | 137 | 138 | 139 | 140 | 141 | 141 | 141 | 141 | 141 | 141 | 141 | 141 | 141 |
+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+
| 141 | 141 | 141 | 141 | 141 | 141 | 141 | 139 | 139 | 139 | 140 | 140 | 141 | 141 | 141 | 140 | 140 | 140 | 140 | 140 | 141 | 142 | 143 | 138 | 138 | 138 | 139 | 139 | 140 | 140 | 140 | 141 | 140 | 139 | 139 | 141 | 141 | 140 | 139 | 145 | 137 | 137 | 145 | 145 | 137 | 137 | 144 | 141 | 139 | 146 | 134 | 145 | 140 | 149 | 144 | 145 | 142 | 140 | 141 | 144 | 145 | 142 | 139 | 140 |
+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+-----+
>>> s2[0,0]
126
>>> s2.save_as("two.csv")
"en una celda" no tiene mucho sentido en el mundo csv. En cualquier caso, su código * SÍ * hace lo que dice que quiere. ¿Cómo está mostrando el archivo de salida? –